In titles that fall under the horror genre, players typically endure chase scenes or are pursued by other characters. However, Grandpa And Granny Two Hunters features a different experience thanks to the fact the player is no longer pursued or captured. Players must discover hidden objects in the environment and become hunting targets. It will be an intense, strategic experience that will challenge them. Players can interact with the environment as Grandpa or Granny, a menacing character who can see and interact with things from a first-person perspective. They will find out exactly who to capture through the cutscenes of each chapter by looking around— players will even see everything in first person. Each character has a different idea of what to do when they're trying to escape your grasp. Make sure to proceed with caution and consider any ideas they have before moving forward.

When beginning the Grandpa and Granny Two Hunters's level, players should first identify the overall quest as well as any additional quests they need to complete. It is also possible to prioritize completing these quests; once players have determined their goals, they should start searching the environment for useful objects. Ensure that no one comes to help you find materials before you look frantically. Different levels feature different tools, obstacles and elements. Additionally, players can find specific objects that determine the game's outcome— such as the communication lines — in each level. Items you find in the area are key in destroying the level. You can only hold one object at a time and must locate the specific location of dropped objects. Subsequently, you must locate these items and use them to destroy the level. As a hunter, you'll need to ensure that the communication line between you and your targets has been cut off. This will motivate you to track down your hidden enemies and locate your weapons. When you discover an enemy, immobilize them with a few seconds of paralysis so that you can capture them and add them to your collection. You can even transport captured enemies in your vehicle to progress through levels. Since speed and accuracy are crucial for both hunters and their prey, this drives the need for both sides to act quickly.

A significant and unavoidable fact presented by Grandpa And Granny Two Hunters is that the game offers two characters to choose from: Grandpa or Granny. Both characters have unique traits that players can customize according to their personal preferences. Grandpa comes equipped with a hammer that renders his opponents immobile. Granny is extremely stealthy and can navigate large areas rapidly. New environments constantly change the playing experience, with new objects and challenges that must be learned to adapt to. Finding new chapters in the game means changing locations and learning new skills. The game features four difficulty levels; players can switch between them at any time. New surprises and difficult puzzles await on the next phase of the game. The intense chase scene inspires players to never stray their gaze. Players assume the roles of Grandpa and Granny, playing two scary characters; they must capture children, obstruct their escape and employ ask-for-help methods. Objectives require the player to search for and interact with specific items found in the environment. If you paralyze your target by attacking them with a weapon, moving them into the vehicle is easy. Playing as this character causes them to have specific traits that influence how they approach the level. Each character offers unique approaches to completing the mission. Changing the difficulty level and exploring new locations constantly alters the experiential results players discover.